Friday, August 19, 2011

Open the mechanism of action of ginkgo on the brain


Has a healing effect on the brain. This plant was used in ancient China, it is used today. But it confirmed the healing properties of little research. Pursuing the study of strokes, a scientist and his colleagues found a mechanism that would deal with the consequences of stroke. They found that mice that lack the enzyme heme observed-oxygenase, poorly restored after a stroke.

This enzyme converts heme (iron-containing compound, a part of many proteins), creating dangerous oxygen radicals, the heme-oxygenase, which - on the contrary, neutralize oxygen radicals. Based on existing studies, Dr. Dore and co-workers made the assumption that increase production of heme-oxygenase and ginkgo may protect brain cells thereby.

To test this idea, they first performed experiments with neurons of the brain, taken from mouse embryos. It was found that cells found in the extract of Ginkgo biloba, less exposed to oxygen radicals than those that were in the normal environment. It is important that very high doses of Ginkgo biloba extract cells provide virtually complete protection.

In the next stage researchers took three groups of living mice. In the first group - mutant mice in which the nature of the heme-oxygenase elaborated a little. The second and third groups - normal mice. First and second group of experiments gave for ginkgo, and the third was a control. After that, all the mice artificially cause a stroke and compared the results.

It was found that mice from the first group to feel worse than rodents in the second. This confirmed the role of heme-oxygenase in the development of stroke. In addition, mice that were not given ginkgo, recovered equally worse than mice in the second group. Thus, the experiment has certified the useful effect of the investigated plants.

These experiments have confirmed the usefulness of rigorous scientific and ginkgo has shown that this herb is a potent neuroprotective.